Option 1: 22 - This option suggests that there are only 22 male science graduates who are not living in urban areas.

Option 2: 23 - This option suggests that there are only 23 male science graduates who are not living in urban areas.

Option 3: 45 - This option is the correct answer. It states that there are 45 male science graduates who are not living in urban areas.

Option 4: 46 - This option suggests that there are 46 male science graduates who are not living in urban areas.

Based on the information provided, option 3 is the correct answer. It states that there are 45 male science graduates who are not living in urban areas. This implies that there is a significant number of male science graduates who have chosen to live in non-urban areas for various reasons.