In the given matching, we need to associate each item in List I (Theory of Mutation, Theory of Evolution, One gene one enzyme hypothesis, Operon concept) with its corresponding scientist or researchers in List II (Beadle and Tatum, Jacob and Monod, Darwin, De Vries).

Let`s go through the options one by one:

Option A: I-C, II-D, III-A, IV-B

- Theory of Mutation (I) - Darwin (C) - Incorrect match

- Theory of Evolution (II) - De Vries (D) - Incorrect match

- One gene one enzyme hypothesis (III) - Beadle and Tatum (A) - Incorrect match

- Operon concept (IV) - Jacob and Monod (B) - Incorrect match

Option B: I-D, II-C, III-A, IV-B

- Theory of Mutation (I) - De Vries (D) - Correct match

- Theory of Evolution (II) - Darwin (C) - Correct match

- One gene one enzyme hypothesis (III) - Beadle and Tatum (A) - Incorrect match

- Operon concept (IV) - Jacob and Monod (B) - Correct match

Option C: I-D, II-C, III-B, IV-A

- Theory of Mutation (I) - De Vries (D) - Correct match

- Theory of Evolution (II) - Darwin (C) - Correct match

- One gene one enzyme hypothesis (III) - Beadle and Tatum (A) - Incorrect match

- Operon concept (IV) - Jacob and Monod (B) - Incorrect match

Option D: I-C, II-D, III-B, IV-A

- Theory of Mutation (I) - Darwin (C) - Incorrect match

- Theory of Evolution (II) - De Vries (D) - Incorrect match

- One gene one enzyme hypothesis (III) - Beadle and Tatum (A) - Incorrect match

- Operon concept (IV) - Jacob and Monod (B) - Incorrect match

Based on the analysis, the correct match is Option B: I-D, II-C, III-A, IV-B. The correct associations are:

- Theory of Mutation (I) - De Vries (D)

- Theory of Evolution (II) - Darwin (C)

- One gene one enzyme hypothesis (III) - Beadle and Tatum (A)

- Operon concept (IV) - Jacob and Monod (B)