The breakdown of glucose in the cytoplasm refers to a process called glycolysis. This process involves the conversion of one molecule of glucose into two molecules of pyruvate. Therefore, option 1, which states that the breakdown of glucose in the cytoplasm results in the formation of pyruvate, is correct.

During glycolysis, glucose is broken down into pyruvate through a series of chemical reactions. This process occurs in the cytoplasm of the cell and does not require oxygen. It is the first step in both aerobic and anaerobic respiration.

In addition to pyruvate, glycolysis also produces a small amount of ATP (adenosine triphosphate), which is the energy currency of the cell. The breakdown of glucose releases energy in the form of ATP, which can be used by the cell for various cellular processes.

Therefore, the breakdown of glucose in the cytoplasm results in the formation of pyruvate and energy.